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Dirk-Jan Reijngoud Selected Research

Acyl-CoA Dehydrogenase (Medium-Chain Acyl-Coenzyme A Dehydrogenase)

12/2016Living on the edge: substrate competition explains loss of robustness in mitochondrial fatty-acid oxidation disorders.
3/2013In vitro and in vivo consequences of variant medium-chain acyl-CoA dehydrogenase genotypes.
5/2012Risk stratification by residual enzyme activity after newborn screening for medium-chain acyl-CoA dehyrogenase deficiency: data from a cohort study.
8/2007Cost-effectiveness of neonatal screening for medium chain acyl-CoA dehydrogenase deficiency: the homogeneous population of The Netherlands.
5/2006The natural history of medium-chain acyl CoA dehydrogenase deficiency in the Netherlands: clinical presentation and outcome.
8/2005The difference between observed and expected prevalence of MCAD deficiency in The Netherlands: a genetic epidemiological study.

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Dirk-Jan Reijngoud Research Topics

Disease

9Phenylketonurias (Phenylketonuria)
02/2015 - 10/2004
7Insulin Resistance
11/2022 - 05/2003
7Medium chain acyl CoA dehydrogenase deficiency
12/2016 - 08/2005
5Hypoglycemia (Reactive Hypoglycemia)
01/2022 - 03/2004
4Metabolic Syndrome (Dysmetabolic Syndrome X)
11/2021 - 01/2014
4Glycogen Storage Disease (Glycogenosis)
01/2021 - 06/2008
4Obesity
01/2021 - 01/2013
4Protein-Energy Malnutrition (Marasmus)
09/2012 - 05/2003
3Fatty Liver
11/2021 - 12/2016
3Mitochondrial Diseases (Mitochondrial Disease)
01/2021 - 04/2010
3Dyslipidemias (Dyslipidemia)
01/2021 - 02/2007
3Malnutrition (Nutritional Deficiencies)
12/2016 - 11/2010
3Hyperglycemia
01/2015 - 02/2007
3Mitochondrial Myopathies (Mitochondrial Myopathy)
05/2002 - 02/2002
2Metabolic Diseases (Metabolic Disease)
01/2022 - 01/2013
2Kwashiorkor
09/2012 - 11/2010
2Cognitive Dysfunction
12/2010 - 02/2009
2Intellectual Disability (Idiocy)
04/2009 - 02/2009
2Hyperlipidemias (Hyperlipidemia)
06/2008 - 02/2007
1Alcoholic Fatty Liver
11/2021
1Fibrosis (Cirrhosis)
11/2021
1Non-alcoholic Fatty Liver Disease
01/2021
1Inborn Errors Metabolism (Inborn Errors of Metabolism)
01/2021
1Hypertriglyceridemia
01/2021
1Multiple Acyl Coenzyme A Dehydrogenase Deficiency
01/2021
1Liver Diseases (Liver Disease)
01/2020
1Melanoma (Melanoma, Malignant)
01/2019
1Hepatorenal form of glycogen storage disease
12/2017
1Sudden Death
12/2017
1Hypoalbuminemia
12/2016
1Hypercholesterolemia
01/2015
1Body Weight (Weight, Body)
01/2014
1Hyperinsulinism (Hyperinsulinemia)
08/2012
1Vitamin B 12 Deficiency (Vitamin B12 Deficiency)
01/2011
1Citrullinemia
12/2010
1Acute Liver Failure (Fulminant Hepatic Failure)
12/2010
1Pantothenate Kinase-Associated Neurodegeneration (Hallervorden-Spatz Disease)
04/2010
1Neurodegenerative Diseases (Neurodegenerative Disease)
04/2010
1Acute-Phase Reaction
06/2008

Drug/Important Bio-Agent (IBA)

11Glucose (Dextrose)FDA LinkGeneric
01/2022 - 03/2004
8Fatty Acids (Saturated Fatty Acids)IBA
11/2022 - 05/2003
8Proteins (Proteins, Gene)FDA Link
11/2022 - 06/2007
8Phenylalanine (L-Phenylalanine)FDA Link
02/2015 - 10/2004
7Insulin (Novolin)FDA Link
11/2022 - 02/2007
7Triglycerides (Triacylglycerol)IBA
11/2021 - 02/2002
6Acyl-CoA Dehydrogenase (Medium-Chain Acyl-Coenzyme A Dehydrogenase)IBA
12/2016 - 08/2005
4Volatile Fatty AcidsIBA
11/2022 - 01/2014
4LipidsIBA
11/2021 - 06/2008
4Amino AcidsFDA Link
02/2015 - 02/2009
4Blood Glucose (Blood Sugar)IBA
08/2012 - 11/2005
3IsotopesIBA
01/2022 - 09/2008
3Dietary FiberFDA Link
07/2015 - 01/2014
3CarbohydratesIBA
12/2010 - 06/2008
2Butyrates (Butyrate)IBA
11/2022 - 11/2021
2Glucose-6-Phosphatase (Glucose 6 Phosphatase)IBA
12/2017 - 12/2010
2Palmitoyl Coenzyme A (Palmitoyl CoA)IBA
12/2016 - 01/2013
2guar gum (guaran)IBA
01/2015 - 01/2014
2Liver GlycogenIBA
12/2013 - 12/2010
2Tyrosine (L-Tyrosine)FDA Link
09/2013 - 04/2009
2Neutral Amino AcidsIBA
09/2013 - 02/2009
2EnzymesIBA
03/2013 - 05/2012
2Prednisolone (Predate)FDA LinkGeneric
08/2012 - 05/2010
2Liver X ReceptorsIBA
12/2010 - 11/2005
1PalmitatesIBA
11/2022
1Messenger RNA (mRNA)IBA
11/2022
1Insulin ReceptorIBA
11/2022
1Oleic Acid (Oleate)IBA
11/2021
1FructoseIBA
11/2021
1Palmitic Acid (Hexadecanoic Acid)IBA
11/2021
1Nonesterified Fatty Acids (NEFA)IBA
01/2021
1Hypoglycemic Agents (Hypoglycemics)IBA
01/2021
1KetonesIBA
01/2021
1VLDL LipoproteinsIBA
01/2021
13-Hydroxybutyric Acid (beta-Hydroxybutyric Acid)IBA
01/2021
1Lipoproteins (Lipoprotein)IBA
01/2020
1Bile Acids and Salts (Bile Acids)IBA
01/2020
1Biological ProductsIBA
01/2019
1acylcarnitineIBA
12/2016
1Adenosine Triphosphate (ATP)IBA
12/2016
1Glucagon-Like Peptide 1 (GLP 1)IBA
01/2015
1AMP-Activated Protein KinasesIBA
01/2015
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
01/2015
1Biomarkers (Surrogate Marker)IBA
01/2014
1Serum AlbuminIBA
09/2012
1Dietary Fats (Dietary Fat)IBA
08/2012
1LeptinIBA
08/2012
1fibroblast growth factor 21IBA
08/2012
1Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric
01/2011
1Carrier Proteins (Binding Protein)IBA
12/2010
1Essential Amino AcidsIBA
12/2010
1Neurotransmitter Agents (Neurotransmitter)IBA
12/2010
1GlucocorticoidsIBA
05/2010
1pantethineIBA
04/2010
1pantothenate kinaseIBA
04/2010
1Coenzyme A (CoA)IBA
04/2010
1IDL Lipoproteins (Lipoprotein, IDL)IBA
06/2008

Therapy/Procedure

2Renal Dialysis (Hemodialysis)
02/2004 - 05/2003
1Glycemic Control
01/2021
1Protein-Restricted Diet (Diet, Protein Restricted)
12/2016
1Liver Transplantation
12/2010